This Assignment is designed to help you analyze the many considerations for prescribing mood stabilizers, as well as organizing the many different lab components to consider when prescribing to a patient.
TO PREPARE
- Review the Required Learning Resources.
- Review indications and considerations for traditionalmood stabilizer psychopharmacology treatments, including carbamazepine, lamotrigine, lithium, and valproate products.
THE ASSIGNMENT:
Construct a 5- to 6-page paper discussing each of the four traditional mood stabilizer medications: carbamazepine, lamotrigine, lithium, and valproate products. Support your answers with five (5) evidence-based, peer-reviewed scholarly literature.
Note: APA style format will apply.
Your paper should include the following for each:
- Proposed mechanism of action
- Baseline assessment, laboratory considerations, and frequency of ongoing labs and assessments
Note:Discuss the importance of assessment and labs. - Special population considerations (birth assigned gender, age, other medical comorbidity considerations)
- FDA approval indications
- Typical dosing with discussion on therapeutic endpoints for psychiatric use
- Major drug–drug interaction considerations
- For each of these medications, please review potential drug–drug interactions listed below. Consider alternative dosing schedules, clinical implications for the drug interactions, additional patient education needed, any additional monitoring recommended, or collaboration needed with other medical professions (such as, primary care providers)
- Lamotrigine + Valproate
- Lamotrigine + Rifampin
- Valproate + Estrogen containing birth control.
- Valproate + Amitriptyline
- Lithium + Furosemide
- Lithium + Lisinopril
- Carbamazepine + Lurasidone
- Carbamazepine + Grapefruit juice
- Discuss the ethical, legal, and social implications related to prescribing bipolar and other related mood-disorder diagnoses therapy for patients.
- For each of these medications, please review potential drug–drug interactions listed below. Consider alternative dosing schedules, clinical implications for the drug interactions, additional patient education needed, any additional monitoring recommended, or collaboration needed with other medical professions (such as, primary care providers)
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. For this Assignment, you are only required to include a title page. The Walden Writing Center Sample PaperLinks to an external site. provides an example of those required elements.
NURS-6630N-19
Introduction
Mood disorders, including bipolar disorder, are complex psychiatric conditions that require careful consideration when prescribing treatment. The pharmacological management of these disorders involves the use of lithium, valproate, carbamazepine, and lamotrigine. Each of the four mood stabilizers has its distinct mechanisms of action, side effects, and drug interactions. This paper will explore the indications, mechanisms, monitoring requirements, and special considerations for these medications, as well as the social, legal, and ethical implications of their use. The purpose of this paper is to describe the comprehensive approach to prescribing therapy for bipolar and related mood-disorder diagnoses.
Elements for Each of the Four Mood Stabilizers
Carbamazepine works by inhibiting voltage-gated Na+ channels, reducing neuronal excitability and bringing mood to a stable level (Sá Filho et al., 2024). A medical history and physical assessment, along with blood tests including LFTs, CBC, thyroid panel, and renal function should be performed at baseline because of risks of hepatotoxicity, blood dyscrasias, and other complications. Regular monitoring is crucial, with LFTs and CBC typically repeated every two-four weeks in the initial months and periodically thereafter……………..KINDLY CLICK THE PURCHASE ICON BELOW TO ACCESS THE ENTIRE SOLUTION FOR $15